Businesses For Sale in Mesa County, CO

Palisade, CO

Own a piece of Palisade wine country - and a business to gowith it! This established income-producing property offers arare opportunity to acquire both the real estate and anoperating hospitality...

$949,000

Available Nationwide

Generate $6.9 million in annual revenue* with America’s premier staffing franchise. Ranked #122 overall on Entrepreneur’s Franchise 500 and a Franchise Business review Top Franchise. Grow your income while empowered by our vibrant, supportive corporate team and franchise community.

$250,000

Grand Junction, CO

Mountain Time Watch Company is a premier, locally owned horology business with a stellar reputation for excellence since 2016. Step into a thriving, completely debt-free business with a literal...

$150,000

Grand Junction, CO

When you’re miles off the grid in the Rockies or braving sub-zero temperatures, gear failure isn’t an option. At Wiggy’s, they don't just sell outdoor gear— they manufacture the most durable, reliable...

$300,000

Grand Junction, CO

An exceptional opportunity to acquire a premier, fully operational specialty market dedicated to the high-demand world of Asian cuisine, culture, and lifestyle. Located in the bustling,...

$90,000

Mesa County, CO

A well established and highly regarded childcare and preschool center in a growing Western Colorado market is available for acquisition for the first time in over three decades. The center has served...

$489,000

Fruita, CO

Doesn't get more Downtown Fruita than this! Located on Aspen Ave and next to City of Fruita parking lot, this building has housed many great business over the years. From Waddell's Market to Kim's...

$92,500,000

Clifton, CO

This established assisted living facility has served ambulatory men and women in Western Colorado for many years, offering a secure, home-based residential care setting supported by a small, dedicated...

$2,250,000

Grand Junction, CO

This established HVAC and refrigeration company provides full-service solutions, including repair, installation, replacement, and maintenance for residential, commercial, and industrial clients. Known...

$575,000

Mesa County, CO

Opportunity to acquire a long-established, multi-disciplinary integrative medical practice serving Western Colorado. Operating for over 20 years, this cash-based clinic delivers personalized,...

$390,000

Mesa County, CO

This is a turnkey, franchise-operated fresh food preparation business specializing in pre-cut fruit, vegetables, and ready-to-eat salads. All products are prepared on-site within grocery store...

$30,000

Palisade, CO

More than a farm and more than a food manufacturing business, Pear Blossom Farms is a proven, scalable business built over 35 years that would be difficult - and expensive to recreate today. Through...

$2,400,000

Available in Colorado

Where Staging Meets Furnishing Needs. Set the Stage is the leader in the Home Staging and Furnishing Sales industry. Since 2016, we’ve tapped into high-demand real estate services with a business that’s simple to launch, fast to scale, and built for recurring revenue. Our proven model combines visually striking staging with a modern retail twist—renters can instantly purchase furniture and décor with a quick QR scan.

$50,000

Grand Junction, CO

Madison Commercial Properties is pleased to present this established liquor store opportunity located in a high-traffic commercial corridor in Western Colorado. Surrounded by strong commercial...

$499,000

Palisade, CO

Sought-after Opportunity in Palisade with major agritourism potential! Located on 2.48 irrigated acres with prime Highway 6 frontage, this high-traffic site offers endless opportunities to expand,...

$1,275,000